General Cell Lines and Cell Cultures
ATCC MDA-MB-231; Breast Adenocarcinoma; Human (Homo sapiens)
For-profit Organizations: For every order of this item, you must work directly with the contributor, MD Anderson Cancer Center to (i) negotiate a research-use license, and/or (ii) have the contributor provide authorization to ATCC to ship this item under your existing license. We cannot ship this item until we receive communication directly from MD Anderson Cancer Center that we are authorized to ship each order. We are providing the following contact information, but this information may change without notice: M.D. Anderson Cancer Center, Office of Technology Commercialization Email: researchtools@mdanderson.org. Once ATCC has received authorization from MD Anderson Cancer Center, your order will be reviewed, and this item will be released for shipment if all requirements are met. If you need assistance with your order, please contact our Customer Care team.
ATCC THP-1 NF-kB-Luc2; Acute Monocytic Leukemia; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
Revvity Health Sciences Inc HTRF IP-One Gq Detection Kit, Standard, 10 Item
HTRF IP-One Gq Detection Kit, Standard, 10 Item
Revvity Health Sciences Inc cAMPZen Frozen Human N-formyl Peptide (FPRL1) Cell Line, CHO-K1 Cells
cAMPZen Frozen Human N-formyl Peptide (FPRL1) Cell Line, CHO-K1 Cells
Revvity Health Sciences Inc cAMPZen Frozen Human Somatostatin sst5 Cell Line, CHO-K1 Cells
cAMPZen Frozen Human Somatostatin sst5 Cell Line, CHO-K1 Cells
Eurofins Discoverx PathHunter CHO-K1 mPTGIR β-Arrestin Cell Pool, 2 vials. (93-0615P2)
The PathHunter mPTGIR cell pool is a stable, engineered cell pool for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell pool enables assessment of ligand (e.g. prostaglandin I2, beraprost) based activation of mPTGIR GPCR activity via detection of β-arrestin recruitment. The included cell pool overexpresses ProLink-tagged mPTGIR and EA-tagged β-Arrestin-2. Activation of mPTGIR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable cell pool is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC hTERT A41hWAT-SVF; Preadipocyte; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
ATCC Acinetobacter baylyi; Strain ADP1 (BD413)
Acinetobacter baylyi strain ADP1 (BD413) is an unencapsulated mutant derived from ATCC 33304. This whole-genome sequenced strain can be used in transformation and gene mapping.
Eurofins Discoverx PathHunter CHO-K1 mOPRK1 β-Arrestin Cell Line, 2 vials. (93-0480C2)
The PathHunter mOPRK1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dynorphin A) based activation of mOPRK1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mOPRK1 and EA-tagged β-Arrestin-2. Activation of mOPRK1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 CXCR3 β-Arrestin Cell Line, 2 vials. (93-0271C2)
The PathHunter CXCR3 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL11/I-TAC) based activation of CXCR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR3 and EA-tagged β-Arrestin-2. Activation of CXCR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC MIA PaCa-2; Pancreatic Carcinoma; Human (Homo sapiens)
MIA PaCa-2 is an epithelial cell that was isolated from the pancreas of a 65-year-old, White male with carcinoma. The cell line can be used in testing and calibration in ISO 17025-accredited laboratories, to challenge assay performance, validate or compare test methods, and establish sensitivity, linearity, and specificity during assay validation or implementation.
ATCC SK-LMS-1; Leiomyosarcoma; Human (Homo sapiens)
SK-LMS-1 is a cell line exhibiting fibroblast morphology that was isolated from the vulva of a 43-year-old, White female patient with leiomyosarcoma. This product has applications in cancer research.
Eurofins Discoverx PathHunter EDG3 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0663C3)
The PathHunter EDG3 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of EDG3 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged EDG3. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting EDG3-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter Jurkat BTLA Signaling Assay, 2 vials. (93-1112C19)
The PathHunter BTLA Checkpoint Signaling cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting signaling checkpoints. This cell line enables assessment of ligand (e.g. HVEM) based activation of BTLA receptors via detection of SH2 domain protein recruitment. The included cell line overexpresses ProLink-tagged BTLA target protein and EA-tagged SH2 domain protein. Upon activation of the receptor by its ligand or an agonist antibody, recruitment of SH2 domain protein to the phosphorylated receptor tail leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.
Eurofins Discoverx PathHunter U2OS PRLR-JAK1 Functional Assay, 2 vials. (93-0686C3)
The PathHunter PRLR-JAK1 Functional assay cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting CTKs. This cell line enables assessment of PRLR activation via detection of JAK1 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged PRLR cytokine receptor, an untagged CTK JAK1 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.